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Miles J. Pfaff, MD

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Miles J. Pfaff, MD, MHS | Orange County Plastic Surgeon

Miles J. Pfaff, MD, MHS is a UC Irvine Health plastic and reconstructive surgeon and assistant professor within the Department of Plastic Surgery at UC Irvine. Dr. Pfaff’s practice is diverse and includes the treatment of craniofacial differences (including cleft lip and palate, craniosynostosis, and ear anomalies), oncologic defects affecting the craniofacial region, facial trauma, and gender-affirmation surgery. Dr. Pfaff also provides surgical and non-surgical aesthetic services.

A southern California native, Dr. Pfaff completed his undergraduate studies in cellular and molecular biology at the University of California, Berkeley. After graduation, Dr. Pfaff spent two years working as a basic science researcher at the University of California, San Francisco investigating novel methods to augment new blood vessel growth. Dr. Pfaff then went on to complete his medical training at Yale School of Medicine. While at Yale, Dr. Pfaff completed a National Institutes of Health research fellowship and earned a Master’s degree focused on investigating the complex biological mechanisms that result in premature suture fusion, also known as craniosynostosis. It was here that he found a passion for both adult and pediatric plastic and reconstructive surgery. Dr. Pfaff then went on to train within the Division of Plastic and Reconstructive Surgery at the University of California, Los Angeles where he earned awards and recognition for excellence in research, education, and patient care. Dr. Pfaff then completed a sub-specialized surgical training fellowship in cleft and craniofacial surgery at Children’s Hospital of Pittsburgh at the University of Pittsburgh’s Department of Plastic Surgery, one of the largest plastic surgery programs in the country.

Dr. Pfaff joined the UC Irvine Department of Plastic Surgery after completing his craniofacial fellowship. He has over one hundred peer-reviewed publications and presentations, is a member of multiple academic surgical societies, and is an active reviewer for professional medical journals. Most importantly, however, Dr. Pfaff is committed to delivering excellent care to his patients. He currently sees patients at the Children’s Hospital of Orange County (CHOC), UC Irvine Medical Center Orange Campus, and the UC Irvine Costa Mesa Clinic.

Clinical Interests and Surgical Services Provided

Research Interests

  • Cleft and craniofacial outcomes
  • Speech surgery outcomes
  • Quality Improvement initiatives
  • Clinical innovation


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